Opening Outlook in Safe Mode can help you troubleshoot problems with the program, such as add-ins or other issues that might be preventing it from functioning properly. Here's a step-by-step guide on how to open Outlook in Safe Mode:

1. Close Outlook if it's currently open.
2. Press and hold the Ctrl on the keyboard.
3. Click the Outlook icon to open the program.
4. You will see a pop-up window asking if you want to start Outlook in Safe Mode. Click "Yes".
5. Once Outlook opens in Safe Mode, you can troubleshoot any issues that may be causing problems.

Note: If you're using Windows 10, you can also open Outlook in Safe Mode by typing "outlook.exe /safe" into the search bar and pressing enter.

In conclusion, opening Outlook in Safe Mode is a great way to troubleshoot any issues you might be having with the program. By following the above step-by-step guide, you can easily open Outlook in Safe Mode and start diagnosing and fixing any problems.