Understanding Glucuronolactone and its Role in the Body

Glucuronolactone, also known as gulonic acid gamma-lactone, is a naturally occurring glucuronide compound that is present in the body. It is a key intermediate in glucose metabolism that is formed through the process of glucuronidation in the liver. Glucuronolactone exists in two enantiomeric forms - D-glucuronolactone and L-glucuronolactone.

D-glucuronolactone is biosynthesized in the liver from glucose through the glucuronidation reaction catalyzed by the enzyme UDP-glucuronosyltransferase. It is formed as an intermediate product during the conversion of glucose to glycogen for storage. Glucuronolactone also plays an important role as an intermediary metabolite in gluconeogenesis when the body needs to produce new glucose from non-carbohydrate sources like proteins or fats.

Glucuronolactone- https://timessquarereporter.co....m/food/glucuronolact

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