Healing Music for Treatment-Resistant Depression
Healing music" is a phrase that gets used loosely — often to describe anything slow, soft, or vaguely spiritual. But in the context of treatment-resistant depression and esketamine therapy, healing music has a more specific meaning. It's music that actively supports the therapeutic process, not just music that feels pleasant. Music therapy research — particularly work coming out of psychedelic-assisted therapy trials at Johns Hopkins, NYU, and Imperial College London — has identified a set of musical qualities that consistently support therapeutic outcomes. These trials use music as an active component of treatment, not background noise, and the playlists are carefully designed. The same principles apply to Spravato® treatment. While esketamine is not a classic psychedelic, it shares the property of increasing neural plasticity and quieting the default mode network — and the music that works best in psychedelic-assisted therapy tends to work well in Spravato® sessions too.
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